Neutrophils Do Not Express IL-17A in the Context of Acute Oropharyngeal Candidiasis

Neutrophils Do Not Express IL-17A in the Context of Acute Oropharyngeal Candidiasis

IL-17 protects against pathogens by acting on nonhematopoietic cells to induce neutrophil recruitment through upregulation of chemokines and G-CSF. IL-17- and Th17-deficient humans and mice are susceptible to mucosal Candida albicans infections, linked to impaired neutrophil responses. IL-17 produc...

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Bibliographic Details
Main Authors: Anna R. Huppler, Akash H. Verma, Heather R. Conti, Sarah L. Gaffen
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Pathogens
Subjects:
IL-17
Th17
Candida albicans
neutrophils
fungal infection
oral candidiasis
innate lymphocyte
TCR
γδ-T cell
mice
Online Access:http://www.mdpi.com/2076-0817/4/3/559

Internet

http://www.mdpi.com/2076-0817/4/3/559

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