Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
<p>Abstract</p> <p>Background</p> <p>While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor and a similar structure; pairwise sequence alignments often fail t...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-03-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/11/146 |