Asymmetric synthesis of host-directed inhibitors of myxoviruses
High-throughput screening (HTS) previously identified benzimidazole 1 (JMN3-003) as a compound with broad antiviral activity against different influenza viruses and paramyxovirus strains. In pursuit of a lead compound from this series for development, we sought to increase both the potency and the a...
Main Authors: | Terry W. Moore, Kasinath Sana, Dan Yan, Pahk Thepchatri, John M. Ndungu, Manohar T. Saindane, Mark A. Lockwood, Michael G. Natchus, Dennis C. Liotta, Richard K. Plemper, James P. Snyder, Aiming Sun |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2013-01-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.9.23 |
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