RNAi-mediated knockdown of cyclooxygenase2 inhibits the growth, invasion and migration of SaOS2 human osteosarcoma cells: a case control study

<p>Abstract</p> <p>Background</p> <p>Cyclooxygenase2 (COX-2), one isoform of cyclooxygenase proinflammatory enzymes, is responsible for tumor development, invasion and metastasis. Due to its role and frequent overexpression in a variety of human malignancies, including...

Full description

Bibliographic Details
Main Authors: Zhang Guoqiao, Dong Shuanghai, Wang Lei, Zhu Jiaxue, Wang Chuan, Zhao Qinghua, Tian Jiwei
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/30/1/26