Antibodies to Citrullinated Proteins (ACPA) Associate with Markers of Osteoclast Activation and Bone Destruction in the Bone Marrow of Patients with Rheumatoid Arthritis

Antibodies to Citrullinated Proteins (ACPA) Associate with Markers of Osteoclast Activation and Bone Destruction in the Bone Marrow of Patients with Rheumatoid Arthritis

Normalizing bone metabolism is a challenge in rheumatoid arthritis (RA). Studies in mice suggest that anti-citrullinated protein antibodies (ACPAs) can trigger osteoclast activation and bone resorption in the bone marrow. However, data on the presence and role of ACPAs in human bone marrow are scarc...

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Bibliographic Details
Main Authors: Weronika Kurowska, Iwona Slowinska, Zbigniew Krogulec, Piotr Syrowka, Wlodzimierz Maslinski
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Journal of Clinical Medicine
Subjects:
rheumatoid arthritis
ACPAs
anti-CCP antibodies
anti-MCV antibodies
bone destruction
bone marrow
Online Access:https://www.mdpi.com/2077-0383/10/8/1778

Internet

https://www.mdpi.com/2077-0383/10/8/1778

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