Sleep and Alzheimer’s Disease
Sleep architecture and sleep patterns normally change with aging. In preclinical Alzheimer’s disease (AD), the accumulation of amyloid plaques begins 10 to 20 years before any cognitive symptoms progress. Soluble amyloid-β (Aβ) is secreted during physiological synaptic activity. Since synaptic activ...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Korean Society of Sleep Medicine
2015-06-01
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Series: | Sleep Medicine Research |
Subjects: | |
Online Access: | http://www.sleepmedres.org/upload/pdf/smr-6-1-1.pdf |