Sleep and Alzheimer’s Disease

Sleep architecture and sleep patterns normally change with aging. In preclinical Alzheimer’s disease (AD), the accumulation of amyloid plaques begins 10 to 20 years before any cognitive symptoms progress. Soluble amyloid-β (Aβ) is secreted during physiological synaptic activity. Since synaptic activ...

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Bibliographic Details
Main Authors: Dongwoo Kang, Hyun Kook Lim, Won Sang Jung, Jong-Hyun Jeong, Tae Won Kim, Jin-Hee Han, Chang Uk Lee, Seung Chul Hong
Format: Article
Language:English
Published: Korean Society of Sleep Medicine 2015-06-01
Series:Sleep Medicine Research
Subjects:
Online Access:http://www.sleepmedres.org/upload/pdf/smr-6-1-1.pdf