Intermittent Hypoxia Influences Alveolar Bone Proper Microstructure via Hypoxia-Inducible Factor and VEGF Expression in Periodontal Ligaments of Growing Rats

Intermittent Hypoxia Influences Alveolar Bone Proper Microstructure via Hypoxia-Inducible Factor and VEGF Expression in Periodontal Ligaments of Growing Rats

Intermittent hypoxia (IH) recapitulates morphological changes in the maxillofacial bones in children with obstructive sleep apnea (OSA). Recently, we found that IH increased bone mineral density (BMD) in the inter-radicular alveolar bone (reflecting enhanced osteogenesis) in the mandibular first mol...

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Bibliographic Details
Main Authors: Shuji Oishi, Yasuhiro Shimizu, Jun Hosomichi, Yoichiro Kuma, Hideyuki Maeda, Hisashi Nagai, Risa Usumi-Fujita, Sawa Kaneko, Naoki Shibutani, Jun-ichi Suzuki, Ken-ichi Yoshida, Takashi Ono
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Physiology
Subjects:
Periodontal Ligament
intermittent hypoxia
Vascular Endothelial Growth Factor
bone mineral density
Hypoxia Inducible Factor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00416/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00416/full

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