Effects of RNA interference-mediated gene silencing of JMJD2A on human breast cancer cell line MDA-MB-231 in vitro

Effects of RNA interference-mediated gene silencing of JMJD2A on human breast cancer cell line MDA-MB-231 in vitro

<p>Abstract</p> <p>Previous data demonstrate that JMJD2A is a cancer-associated gene and may be involved in human breast cancer by demethylation of H3K9me3. The aim of this study was to investigate depressive effects on JMJD2A by transfection with JMJD2A-sepcific siRNA in human bre...

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Bibliographic Details
Main Authors: Shen Yi-Wen, Xu Hong-Fei, Xu Hong-Mei, Li Hui, Yang Peng, Luo Cheng-Liang, Zhang Ming-Chang, Li Bei-Xu, Xue Ai-Min, Zhao Zi-Qin
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
JMJD2A
transfection
proliferation
invasion
migration
Online Access:http://www.jeccr.com/content/30/1/90

Internet

http://www.jeccr.com/content/30/1/90

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