Biogenic nanoporous silicon carrier improves the efficacy of buparvaquone against resistant visceral leishmaniasis.

Visceral leishmaniasis is a vector-borne protozoan infection that is fatal if untreated. There is no vaccination against the disease, and the current chemotherapeutic agents are ineffective due to increased resistance and severe side effects. Buparvaquone is a potential drug against the leishmaniase...

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Bibliographic Details
Main Authors: Rinez Thapa, Subhasish Mondal, Joakim Riikonen, Jimi Rantanen, Simo Näkki, Tuomo Nissinen, Ale Närvänen, Vesa-Pekka Lehto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009533