Ubiquitin-regulated nuclear-cytoplasmic trafficking of the Nipah virus matrix protein is important for viral budding.

Paramyxoviruses are known to replicate in the cytoplasm and bud from the plasma membrane. Matrix is the major structural protein in paramyxoviruses that mediates viral assembly and budding. Curiously, the matrix proteins of a few paramyxoviruses have been found in the nucleus, although the biologica...

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Bibliographic Details
Main Authors: Yao E Wang, Arnold Park, Michael Lake, Mickey Pentecost, Betsabe Torres, Tatyana E Yun, Mike C Wolf, Michael R Holbrook, Alexander N Freiberg, Benhur Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2978725?pdf=render