Significant Suppression of Non-small-cell Lung Cancer by Hydrophobic Poly(ester amide) Nanoparticles with High Docetaxel Loading

Significant Suppression of Non-small-cell Lung Cancer by Hydrophobic Poly(ester amide) Nanoparticles with High Docetaxel Loading

Non-small-cell lung cancer (NSCLC) accounts for over 85% of clinical lung cancer cases, which is the leading cause of cancer-related death. To develop new therapeutic strategy for NSCLC, a library of L-phenylalanine-based poly(ester amide) (Phe-PEA) polymers was synthesized and assembled with doceta...

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Bibliographic Details
Main Authors: Xing Chen, Lili Zhao, Yang Kang, Zhiyu He, Fei Xiong, Xiang Ling, Jun Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
Subjects:
cancer
docetaxel
hydrophobicity
nanoparticle
poly(ester amide)
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00118/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00118/full

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