Derivation of Haploid Trophoblast Stem Cells via Conversion In Vitro

Summary: Owing to their single genome, haploid cells are powerful to uncover unknown genes by performing genetic screening in mammals. However, no haploid cell line from an extraembryonic lineage has been achieved yet, which limits the application of haploid cells in placental genetic screening. Her...

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Bibliographic Details
Main Authors: Keli Peng, Xu Li, Congyu Wu, Yuna Wang, Jian Yu, Jinxin Zhang, Qian Gao, Wenhao Zhang, Qian Zhang, Yong Fan, Yang Yu, Ling Shuai
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218302438