Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.

Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.

Macrophage stimulating protein (MSP) is a serum growth factor that binds to and activates the receptor tyrosine kinase, Recepteur d'Origine Nantais (RON). A non-synonymous coding variant in MSP (689C) has been associated with genetic susceptibility to both Crohn's disease and ulcerative co...

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Bibliographic Details
Main Authors: Steven E Kauder, Lydia Santell, Elaine Mai, Lilyan Y Wright, Elizabeth Luis, Elsa N N'Diaye, Jeff Lutman, Navneet Ratti, Susan M Sa, Henry R Maun, Eric Stefanich, Lino C Gonzalez, Robert R Graham, Lauri Diehl, William A Faubion, Mary E Keir, Judy Young, Amitabha Chaudhuri, Robert A Lazarus, Jackson G Egen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3884107?pdf=render

Internet

http://europepmc.org/articles/PMC3884107?pdf=render

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