TREM2 Mediates Microglial Anti-Inflammatory Activations in Alzheimer’s Disease: Lessons Learned from Transcriptomics

Alzheimer’s disease (AD) is a lethal neurodegenerative disorder primarily affecting the aged population. The etiopathogenesis of AD, especially that of the sporadic type, remains elusive. The triggering receptor expressed on myeloid cells 2 (TREM2), a member of TREM immunoglobulin superfamily, plays...

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Bibliographic Details
Main Authors: Feng Xue, Heng Du
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/2/321