Distinct immune signatures in chronic lymphocytic leukemia and Richter syndrome

Distinct immune signatures in chronic lymphocytic leukemia and Richter syndrome

Abstract Richter syndrome (RS) refers to transformation of chronic lymphocytic leukemia (CLL) to an aggressive lymphoma, most commonly diffuse large B-cell lymphoma. RS is known to be associated with a number of genetic alterations such as TP53 and NOTCH1 mutations. However, it is unclear what immun...

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Bibliographic Details
Main Authors: Yucai Wang, Sutapa Sinha, Linda E. Wellik, Charla R. Secreto, Karen L. Rech, Timothy G. Call, Sameer A. Parikh, Saad S. Kenderian, Eli Muchtar, Suzanne R. Hayman, Amber B. Koehler, Daniel L. Van Dyke, Jose F. Leis, Susan L. Slager, Haidong Dong, Neil E. Kay, Rong He, Wei Ding
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-021-00477-5

Internet

https://doi.org/10.1038/s41408-021-00477-5

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