An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils

An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils

For the treatment of monogenetic hematological disorders, restoration of transgene expression in affected cell populations is generally considered to have beneficial effects. However, X-linked chronic granulomatous disease (XCGD) is unique since the appearance of functional neutrophils in the periph...

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Main Authors: Huan-Ting Lin, Hideki Masaki, Tomoyuki Yamaguchi, Taizo Wada, Akihiro Yachie, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Hiromitsu Nakauchi, Makoto Otsu
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050116300584

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http://www.sciencedirect.com/science/article/pii/S2329050116300584

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