The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers.

The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers.

Clinical observations and mouse models have suggested that inflammation can be pro-tumorigenic. Since chemokines are critical in leukocyte trafficking, we hypothesized that chemokines play essential roles in inflammation-associated cancers. Screening for 37 chemokines in prostate cancer cell lines a...

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Bibliographic Details
Main Authors: Merav Darash-Yahana, John W Gillespie, Stephen M Hewitt, Yun-Yun K Chen, Shin Maeda, Ilan Stein, Satya P Singh, Roble B Bedolla, Amnon Peled, Dean A Troyer, Eli Pikarsky, Michael Karin, Joshua M Farber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2723911?pdf=render

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http://europepmc.org/articles/PMC2723911?pdf=render

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