Molecular networking in the neuronal ceroid lipofuscinoses: insights from mammalian models and the social amoeba Dictyostelium discoideum

Molecular networking in the neuronal ceroid lipofuscinoses: insights from mammalian models and the social amoeba Dictyostelium discoideum

Abstract The neuronal ceroid lipofuscinoses (NCLs), commonly known as Batten disease, belong to a family of neurological disorders that cause blindness, seizures, loss of motor function and cognitive ability, and premature death. There are 13 different subtypes of NCL that are associated with mutati...

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Bibliographic Details
Main Author: Robert J. Huber
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Biomedical Science
Subjects:
Neuronal ceroid lipofuscinosis
Batten disease
Dictyostelium discoideum
 Molecular networking
Neurodegeneration
Online Access:http://link.springer.com/article/10.1186/s12929-020-00653-y

Internet

http://link.springer.com/article/10.1186/s12929-020-00653-y

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