Immunogenicity and protective response induced by recombinant plasmids based on the BAB1_0267 and BAB1_0270 open reading frames of Brucella abortus 2308 in BALB/c mice.

Immunogenicity and protective response induced by recombinant plasmids based on the BAB1_0267 and BAB1_0270 open reading frames of Brucella abortus 2308 in BALB/c mice.

Immunogenicity induced by recombinant plasmids based on the BAB1_0267 and BAB1_0270 open reading frames (ORFs) of Brucella abortus 2308 was evaluated. Bioinformatics analyses indicate that the BAB1_0267 and BAB1_0270 ORFs encode a protein with a SH3 domain and a Zn-dependent metalloproteinase, respe...

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Bibliographic Details
Main Authors: Leonardo Antonio Gomez, Francisco Ignacio Alvarez, Pablo Antonio Fernandez, Manuel Rodrigo Flores, Raúl Enrique Molina, Roberto Felipe Coloma, Angel Alejandro Oñate
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Brucella abortus
Brucellosis
DNA Vaccines
Src homology 3 domain
Zinc metalloproteinase
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00117/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00117/full

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