Maternal caloric restriction implemented during the preconceptional and pregnancy period alters hypothalamic and hippocampal endocannabinoid levels at birth and induces overweight and increased adiposity at adulthood in male rat offspring

Maternal caloric restriction implemented during the preconceptional and pregnancy period alters hypothalamic and hippocampal endocannabinoid levels at birth and induces overweight and increased adiposity at adulthood in male rat offspring

Exposure to inadequate nutritional conditions in critical windows of development has been associated to disturbances on metabolism and behavior in the offspring later in life. The role of the endocannabinoid system, a known regulator of energy expenditure and adaptive behaviors, in the modulation of...

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Bibliographic Details
Main Authors: MARÍA TERESA RAMÍREZ-LÓPEZ, Mariam Vazquez, Laura Bindila, Ermelinda Lomazzo, Clementine Hofmann, Noemi Blanco, Francisco Alen, MARIA ANTÓN, Juan Decara, Rocío Arco, Daniel Ouro, LAURA ORIO, JUAN SUAREZ, Beat Lutz, Raquel Gomez de Heras, FERNANDO RODRIGUEZ DE FONSECA
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Behavior
Endocannabinoids
Hippocampus
Hypothalamus
Metabolism
Olfactory Bulb
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00208/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00208/full

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