A single gp120 residue can affect HIV-1 tropism in macaques.

A single gp120 residue can affect HIV-1 tropism in macaques.

Species-dependent variation in proteins that aid or limit virus replication determines the ability of lentiviruses to jump between host species. Identifying and overcoming these differences facilitates the development of animal models for HIV-1, including models based on chimeric SIVs that express H...

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Bibliographic Details
Main Authors: Gregory Q Del Prete, Brandon F Keele, Jeannine Fode, Keyur Thummar, Adrienne E Swanstrom, Anthony Rodriguez, Alice Raymond, Jacob D Estes, Celia C LaBranche, David C Montefiori, Vineet N KewalRamani, Jeffrey D Lifson, Paul D Bieniasz, Theodora Hatziioannou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5629034?pdf=render

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http://europepmc.org/articles/PMC5629034?pdf=render

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