Prediction and dissection of widely-varying association rate constants of actin-binding proteins.

Actin is an abundant protein that constitutes a main component of the eukaryotic cytoskeleton. Its polymerization and depolymerization are regulated by a variety of actin-binding proteins. Their functions range from nucleation of actin polymerization to sequestering G-actin in 1∶1 complexes. The kin...

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Bibliographic Details
Main Authors: Xiaodong Pang, Kenneth H Zhou, Sanbo Qin, Huan-Xiang Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3464195?pdf=render