Co-diversification of Enterococcus faecium core genomes and PBP5: evidences of pbp5 horizontal transfer

Co-diversification of Enterococcus faecium core genomes and PBP5: evidences of pbp5 horizontal transfer

Ampicillin resistance has greatly contributed to the recent dramatic increase of a cluster of human adapted Enterococcus faecium lineages (ST17, ST18 and ST78) in hospital-based infections. Changes in the chromosomal pbp5 gene have been associated with different levels of ampicillin susceptibility,...

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Bibliographic Details
Main Authors: Carla Novais, Ana P. Tedim, Val F. Lanza, Ana R. Freitas, Eduarda Silveira, Ricardo Escada, Adam Paul Roberts, Mohammed Al-Haroni, Fernando Baquero, Luísa Peixe, Teresa M. Coque
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Microbiology
Subjects:
Ampicillin Resistance
PONA
PBP5 mutations
chromosomal transfer
phylogenomic diversification
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01581/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01581/full

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