Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab

<p>Abstract</p> <p>Background</p> <p>Responsiveness to Cetuximab alone can be mediated by an increase of Epidermal Growth factor Receptor (EGFR) Gene Copy Number (GCN). Aim of this study was to assess the role of EGFR-GCN in advanced colorectal cancer (CRC) patients rec...

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Main Authors: Zeuli Massimo, Diodoro Maria, Conti Salvatore, Melucci Elisa, Sperduti Isabella, Merola Roberta, Torsello Angela, Cianciulli Anna, Mottolese Marcella, Campanella Carla, Paoletti Giancarlo, Cognetti Francesco, Garufi Carlo
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/36