Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways

Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways

<p>Abstract</p> <p>Human T-cell leukemia virus type-1 (HTLV-1) induces adult T-cell leukemia/lymphoma (ATL/L), a fatal lymphoproliferative disorder, and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic progressive disease of the central nervous system...

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Bibliographic Details
Main Authors: Wu Weilin, Kehn-Hall Kyleen, Pedati Caitlin, Klase Zachary, Berro Reem, Yeh Wen-I, Agbottah Emmanuel, Kashanchi Fatah
Format: Article
Language:English
Published: BMC 2008-06-01
Series:AIDS Research and Therapy
Online Access:http://www.aidsrestherapy.com/content/5/1/12

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http://www.aidsrestherapy.com/content/5/1/12

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