Rapid Dendritic Cell Activation and Resistance to Allotolerance Induction in Anti-CD154-Treated Mice Receiving CD47-Deficient Donor-Specific Transfusion

CD47–SIRPα signaling plays an important role in regulating macrophage and dendritic cell (DC) activation. Here we investigated the role of CD47 expression on donor cells in tolerance induction by combined treatment with donor-specific transfusion (DST) plus anti-CD154 mAb in a mouse model of fully M...

Full description

Bibliographic Details
Main Authors: Yuantao Wang, Hui Wang, Roderick Bronson, Yaowen Fu M.D., Ph.D., Yong-Guang Yang M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2014-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X661346