A neurotoxin that specifically targets Anopheles mosquitoes

So far identified clostridial neurotoxins target vertebrates. Here, Contreras et al. isolate the clostridial-like neurotoxin PMP1 from Paraclostridium bifermentans strains and show that it selectively targets anopheline mosquitoes by targeting mosquito syntaxin.

Bibliographic Details
Main Authors:	Estefania Contreras, Geoffrey Masuyer, Nadia Qureshi, Swati Chawla, Harpal S. Dhillon, Han Lim Lee, Jianwu Chen, Pål Stenmark, Sarjeet S. Gill
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019-06-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-10732-w

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spelling	doaj-6b5342a9ac424bdc98b2c66bd095f8192021-05-11T12:05:06ZengNature Publishing GroupNature Communications2041-17232019-06-0110111010.1038/s41467-019-10732-wA neurotoxin that specifically targets Anopheles mosquitoesEstefania Contreras0Geoffrey Masuyer1Nadia Qureshi2Swati Chawla3Harpal S. Dhillon4Han Lim Lee5Jianwu Chen6Pål Stenmark7Sarjeet S. Gill8Department of Molecular, Cell and Systems Biology, University of CaliforniaDepartment of Biochemistry and Biophysics, Stockholm UniversityDepartment of Molecular, Cell and Systems Biology, University of CaliforniaDepartment of Molecular, Cell and Systems Biology, University of CaliforniaDepartment of Molecular, Cell and Systems Biology, University of CaliforniaUnit of Medical Entomology, Institute for Medical ResearchDepartment of Molecular, Cell and Systems Biology, University of CaliforniaDepartment of Biochemistry and Biophysics, Stockholm UniversityDepartment of Molecular, Cell and Systems Biology, University of CaliforniaSo far identified clostridial neurotoxins target vertebrates. Here, Contreras et al. isolate the clostridial-like neurotoxin PMP1 from Paraclostridium bifermentans strains and show that it selectively targets anopheline mosquitoes by targeting mosquito syntaxin.https://doi.org/10.1038/s41467-019-10732-w
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Estefania Contreras Geoffrey Masuyer Nadia Qureshi Swati Chawla Harpal S. Dhillon Han Lim Lee Jianwu Chen Pål Stenmark Sarjeet S. Gill
spellingShingle	Estefania Contreras Geoffrey Masuyer Nadia Qureshi Swati Chawla Harpal S. Dhillon Han Lim Lee Jianwu Chen Pål Stenmark Sarjeet S. Gill A neurotoxin that specifically targets Anopheles mosquitoes Nature Communications
author_facet	Estefania Contreras Geoffrey Masuyer Nadia Qureshi Swati Chawla Harpal S. Dhillon Han Lim Lee Jianwu Chen Pål Stenmark Sarjeet S. Gill
author_sort	Estefania Contreras
title	A neurotoxin that specifically targets Anopheles mosquitoes
title_short	A neurotoxin that specifically targets Anopheles mosquitoes
title_full	A neurotoxin that specifically targets Anopheles mosquitoes
title_fullStr	A neurotoxin that specifically targets Anopheles mosquitoes
title_full_unstemmed	A neurotoxin that specifically targets Anopheles mosquitoes
title_sort	neurotoxin that specifically targets anopheles mosquitoes
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2019-06-01
description	So far identified clostridial neurotoxins target vertebrates. Here, Contreras et al. isolate the clostridial-like neurotoxin PMP1 from Paraclostridium bifermentans strains and show that it selectively targets anopheline mosquitoes by targeting mosquito syntaxin.
url	https://doi.org/10.1038/s41467-019-10732-w
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A neurotoxin that specifically targets Anopheles mosquitoes

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