Mucin 4 Gene Silencing Reduces Oxidative Stress and Calcium Oxalate Crystal Formation in Renal Tubular Epithelial Cells Through the Extracellular Signal-Regulated Kinase Signaling Pathway in Nephrolithiasis Rat Model

Mucin 4 Gene Silencing Reduces Oxidative Stress and Calcium Oxalate Crystal Formation in Renal Tubular Epithelial Cells Through the Extracellular Signal-Regulated Kinase Signaling Pathway in Nephrolithiasis Rat Model

Background/Aims: Nephrolithiasis plagues a great number of patients all over the world. Increasing evidence shows that the extracellular signal-regulated kinase (ERK) signaling pathway and renal tubular epithelial cell (RTEC) dysfunction and attrition are central to the pathogenesis of kidney diseas...

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Bibliographic Details
Main Authors: Ling Sun, Lu-Xi Zou, Jie Wang, Ting Chen, Yu-Chen Han, Dong-Dong Zhu, Shi-Chao Zhuo
Format: Article
Language:English
Published: Karger Publishers 2018-05-01
Series:Kidney & Blood Pressure Research
Subjects:
Mucin 4
Extracellular signal-regulated kinase signaling pathway
Oxidative stress
Calcium oxalate crystal formation
Renal tubular epithelial cell
Nephrolithiasis
Online Access:https://www.karger.com/Article/FullText/490136

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https://www.karger.com/Article/FullText/490136

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