Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease

Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease

Abstract Background Tau pathology is a hallmark of Alzheimer’s disease (AD) and other tauopathies. During disease progression, abnormally phosphorylated forms of tau aggregate and accumulate into neurofibrillary tangles, leading to synapse loss, neuroinflammation, and neurodegeneration. Thus, target...

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Bibliographic Details
Main Authors: Xiao-ying Sun, Ling-jie Li, Quan-Xiu Dong, Jie Zhu, Ya-ru Huang, Sheng-jie Hou, Xiao-lin Yu, Rui-tian Liu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Neuroinflammation
Subjects:
Alzheimer’s disease
Tau pathology
Neurofibrillary tangles
Neuroinflammation
Synapse loss
Rutin
Online Access:https://doi.org/10.1186/s12974-021-02182-3

Internet

https://doi.org/10.1186/s12974-021-02182-3

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