Localization Microscopy Analyses of MRE11 Clusters in 3D-Conserved Cell Nuclei of Different Cell Lines

Localization Microscopy Analyses of MRE11 Clusters in 3D-Conserved Cell Nuclei of Different Cell Lines

In radiation biophysics, it is a subject of nowadays research to investigate DNA strand break repair in detail after damage induction by ionizing radiation. It is a subject of debate as to what makes up the cell’s decision to use a certain repair pathway and how the repair machinery recruited in rep...

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Bibliographic Details
Main Authors: Marion Eryilmaz, Eberhard Schmitt, Matthias Krufczik, Franziska Theda, Jin-Ho Lee, Christoph Cremer, Felix Bestvater, Wladimir Schaufler, Michael Hausmann, Georg Hildenbrand
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Cancers
Subjects:
single-molecule localization microscopy
nano-distance analysis
MRE11 repair foci
DNA damaging
DNA repair
H2AX phosphorylation
γH2AX formation
Online Access:http://www.mdpi.com/2072-6694/10/1/25

Internet

http://www.mdpi.com/2072-6694/10/1/25

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