Age-dependent recombination rates in human pedigrees.

In humans, chromosome-number abnormalities have been associated with altered recombination and increased maternal age. Therefore, age-related effects on recombination are of major importance, especially in relation to the mechanisms involved in human trisomies. Here, we examine the relationship betw...

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Bibliographic Details
Main Authors: Julie Hussin, Marie-Hélène Roy-Gagnon, Roxanne Gendron, Gregor Andelfinger, Philip Awadalla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3164683?pdf=render