Matrix Metalloproteinase-3 (MMP-3) Is an Endogenous Activator of the MMP-9 Secreted by Placental Leukocytes: Implication in Human Labor.

BACKGROUND:The activity of matrix degrading enzymes plays a leading role in the rupture of the fetal membranes under normal and pathological human labor, and matrix metalloproteinase-9 (MMP-9) it is considered a biomarker of this event. To gain further insight into local MMP-9 origin and activation,...

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Main Authors: Arturo Flores-Pliego, Aurora Espejel-Nuñez, Marisol Castillo-Castrejon, Noemi Meraz-Cruz, Jorge Beltran-Montoya, Veronica Zaga-Clavellina, Sonia Nava-Salazar, Maribel Sanchez-Martinez, Felipe Vadillo-Ortega, Guadalupe Estrada-Gutierrez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4699849?pdf=render