Losartan inhibits hyposmotic-induced increase of IKs current and shortening of action potential duration in guinea pig atrial myocytes

Objective: The present study aims to investigate the effect of losartan, an selective angiotensin II type 1 receptor (AT1R) blocker, on both the increase of IKs current and shortening of action potential duration (APD) induced by stretch of atrial myocytes, and to uncover the mechanism underlying th...

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Bibliographic Details
Main Authors: Jie Gao, Yun Tian, Xiaolu Xie, Jin Zhao, Chuan-hao Liu, Ying Sheng, Fang Cao
Format: Article
Language:English
Published: KARE Publishing 2019-12-01
Series:Anatolian Journal of Cardiology
Subjects:
iks
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=anatoljcardiol&un=AJC-75332