Integrating readout of somatic mutations in individual cells with single-cell transcriptional profiling

Integrating readout of somatic mutations in individual cells with single-cell transcriptional profiling

Summary: In many biological applications, the readout of somatic mutations in individual cells is essential. For example, it can be used to mark individual cancer cells or identify progenies of a stem cell. Here, we present a protocol to perform single-cell RNA-seq and single-cell amplicon-seq using...

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Bibliographic Details
Main Authors: Shichen Liu, Maximilian Nguyen, Sahand Hormoz
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:STAR Protocols
Subjects:
Bioinformatics
Cell isolation
Single Cell
Cancer
Genomics
RNA-seq
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721003804

Internet

http://www.sciencedirect.com/science/article/pii/S2666166721003804

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