Crohn's disease is facilitated by a disturbance of programmed death‐1 ligand 2 on blood dendritic cells

Abstract Objective Crohn's disease (CD) is characterised by inflammation, predominantly associated with ilea. To investigate the basis for this inflammation in patients with CD, we examined dendritic cells (DC) which are pivotal for maintenance of immunological tolerance in the gut. Methods Ile...

Full description

Bibliographic Details
Main Authors: Rebecca Faleiro, Ji Liu, Deshapriya Karunarathne, Aleksandra Edmundson, Clay Winterford, Tam Hong Nguyen, Lisa A Simms, Graham Radford‐Smith, Michelle Wykes
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Clinical & Translational Immunology
Subjects:
Online Access:https://doi.org/10.1002/cti2.1071