Variance heterogeneity in Saccharomyces cerevisiae expression data: trans-regulation and epistasis.

Here, we describe the results from the first variance heterogeneity Genome Wide Association Study (VGWAS) on yeast expression data. Using this forward genetics approach, we show that the genetic regulation of gene-expression in the budding yeast, Saccharomyces cerevisiae, includes mechanisms that ca...

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Bibliographic Details
Main Authors: Ronald M Nelson, Mats E Pettersson, Xidan Li, Örjan Carlborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3817098?pdf=render