Rapamycin Protects Against Peritendinous Fibrosis Through Activation of Autophagy

Dysregulation of autophagy plays a pivotal role in fibrosis in multiple organs. However, the role of autophagy in peritendinous fibrosis is not well understood. Here, we hypothesize that autophagy plays a protective role in preventing adhesion formation. In a rat model of tendon injury, we observed...

Full description

Bibliographic Details
Main Authors: Wei Zheng, Yun Qian, Shuai Chen, Hongjiang Ruan, Cunyi Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00402/full