High throughput evaluation of gamma-H2AX

<p>Abstract</p> <p>The DNA double-strand break (DSB) is the primary lethal lesion after therapeutic radiation. Thus, the development of assays to detect and to quantitate these lesions could have broad preclinical and clinical impact. Phosphorylation of histone H2AX to form γ-H2AX...

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Bibliographic Details
Main Authors: Tofilon Philip J, Sproull Mary, Kil Whoon, Scott Tamalee, Avondoglio Dane, Camphausen Kevin
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Radiation Oncology
Online Access:http://www.ro-journal.com/content/4/1/31