Lower IgA Levels in Chronic Spontaneous Urticaria Are Associated With Lower IgE Levels and Autoimmunity

Lower IgA Levels in Chronic Spontaneous Urticaria Are Associated With Lower IgE Levels and Autoimmunity

BackgroundThe pathogenesis of chronic spontaneous urticaria (CSU) is still insufficiently understood. Recent findings suggest that immunoglobulins, in particular IgE but also IgA, play a role in the development of CSU.ObjectiveOur aim was to assess differences in clinical and laboratory markers betw...

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Bibliographic Details
Main Authors: Merle Sauer, Jörg Scheffel, Stefan Frischbutter, Pavel Kolkhir, Yi-Kui Xiang, Frank Siebenhaar, Sabine Altrichter, Marcus Maurer, Martin Metz, Karoline Krause
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
immunoglobulin A
immunoglobulin E
chronic spontaneous urticaria
autoreactivity
autoimmune disease
basophils
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.657211/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.657211/full

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