FIBROBLAST INVOLVEMENT IN SOFT CONNECTIVE TISSUE CALCIFICATION

Soft connective tissue calcification is not a passive process, but the consequence of metabolic changes of local mesenchymal cells that, depending on both genetic and environmental factors, alter the balance between pro- and anti-calcifying pathways. While the role of smooth muscle cells and pericyt...

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Bibliographic Details
Main Authors: Ivonne eRonchetti, Federica eBoraldi, Giulia eAnnovi, Paolo eCianciulli, Daniela eQuaglino
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Genetics
Subjects:
PXE
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00022/full