Hepatic Transcriptome Analysis Revealing the Molecular Pathogenesis of Type 2 Diabetes Mellitus in Zucker Diabetic Fatty Rats

Hepatic Transcriptome Analysis Revealing the Molecular Pathogenesis of Type 2 Diabetes Mellitus in Zucker Diabetic Fatty Rats

Around 9% of the adult population in the world (463 million) suffer from diabetes mellitus. Most of them (~90%) belong to type 2 diabetes mellitus (T2DM), which is a common chronic metabolic disorder, and the number of cases has been reported to increase each year. Zucker diabetic fatty (ZDF) rat pr...

Full description

Bibliographic Details
Main Authors: Chengdong Xia, Xiuli Zhang, Tianshu Cao, Jiannong Wang, Cuidan Li, Liya Yue, Kaifeng Niu, Yicheng Shen, Guannan Ma, Fei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Endocrinology
Subjects:
type 2 diabetes mellitus (T2DM)
molecular pathogenesis
substance metabolism
inflammation
liver injury
ER stress
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.565858/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2020.565858/full

Similar Items