USP5 Sustains the Proliferation of Glioblastoma Through Stabilization of CyclinD1

USP5 Sustains the Proliferation of Glioblastoma Through Stabilization of CyclinD1

Glioblastoma multiforme (GBM) is one of the most malignant primary tumors in humans. Despite standard therapeutic strategy with tumor resection combined with radiochemotherapy, the prognosis remains disappointed. Recently, deubiquitinating enzymes (DUBs) has been reported as potential cancer therapy...

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Bibliographic Details
Main Authors: Gen Li, Tianquan Yang, Yanling Chen, Jianping Bao, Di Wu, Xiaohan Hu, Chenxi Feng, Lixiao Xu, Mei Li, Gang Li, Meifang Jin, Yunyun Xu, Rui Zhang, Guanghui Qian, Jian Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
glioblastoma multiforme
USP5
CyclinD1
deubiquitination
cell cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.720307/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.720307/full

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