Development and Selection of the Human Vγ9Vδ2+ T-Cell Repertoire

Vγ9Vδ2+ lymphocytes are among the first T-cells to develop in the human fetus and are the predominant peripheral blood γδ T-cell population in most adults. Capable of broad polyclonal responses to pyrophosphate antigens (pAg), they are implicated in immunity to a diverse range of infections. Previou...

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Bibliographic Details
Main Authors: Carrie R. Willcox, Martin S. Davey, Benjamin E. Willcox
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01501/full