Akt-Fas to Quell Aberrant T Cell Differentiation and Apoptosis in Covid-19

Aberrant T cell differentiation and lymphopenia are hallmarks of severe COVID-19 disease. Since T cells must race to cull infected cells, they are quick to differentiate and achieve cytotoxic function. With this responsiveness, comes hastened apoptosis, due to a coupled mechanism of death and differ...

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Bibliographic Details
Main Authors: Anthony J. Leonardi, Rui B. Proenca
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
Akt
Fas
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.600405/full