The Retinoic Acid Receptor-α mediates human T-cell activation and Th2 cytokine and chemokine production

<p>Abstract</p> <p>Background</p> <p>We have recently demonstrated that all-<it>trans</it>-retinoic acid (ATRA) and 9-cis-retinoic acid (9-<it>cis </it>RA) promote IL-4, IL-5 and IL-13 synthesis, while decreasing IFN-γ and TNF-α expression by act...

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Bibliographic Details
Main Authors: Key Michael, Pyle Robert, Collins Gary, Dawson Harry D, Taub Dennis D
Format: Article
Language:English
Published: BMC 2008-04-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/9/16