A Spectrum of Neural Autoantigens, Newly Identified by Histo-Immunoprecipitation, Mass Spectrometry, and Recombinant Cell-Based Indirect Immunofluorescence

A Spectrum of Neural Autoantigens, Newly Identified by Histo-Immunoprecipitation, Mass Spectrometry, and Recombinant Cell-Based Indirect Immunofluorescence

BackgroundA plurality of neurological syndromes is associated with autoantibodies against neural antigens relevant for diagnosis and therapy. Identification of these antigens is crucial to understand the pathogenesis and to develop specific immunoassays. Using an indirect immunofluorescence assay (I...

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Bibliographic Details
Main Authors: Madeleine Scharf, Ramona Miske, Stephanie Kade, Stefanie Hahn, Yvonne Denno, Nora Begemann, Nadine Rochow, Christiane Radzimski, Stephanie Brakopp, Christian Probst, Bianca Teegen, Winfried Stöcker, Lars Komorowski
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
neural autoantibodies
immunoprecipitation
antigen identification
autoantigens
indirect immunofluorescence
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01447/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01447/full

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