The role of animal models in the study of hematopoietic stem cell transplantation and GvHD: A historical overview.

Bone marrow transplantation (BMT) is the only therapeutic option for many hematological malignancies, but its applicability is limited by life-threatening complications such as graft-versus-host disease (GvHD). The last decades have seen great advances in the understanding of BMT and its related com...

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Bibliographic Details
Main Authors: Margherita Boieri, Pranali Shah, Ralf Dressel, Marit Inngjerdingen
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00333/full