Activated E2F activity induces cell death in papillary thyroid carcinoma K1 cells with enhanced Wnt signaling.

Disruption of Wnt signaling often happens in tumorigenesis, but whether Wnt signaling affects the early stages of thyroid tumor, such as papillary thyroid carcinoma, is still a question, especially in the papillary thyroid carcinoma without genomic RET/PTC mutation. In this study, we demonstrated th...

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Bibliographic Details
Main Authors: Dong Yang, Chuanjiang Wang, Yingwei Luo, Xuan Li, Qingbin Song, Jian Zhang, Shijie Xin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5453581?pdf=render