Alterations of choroidal blood flow regulation in young healthy subjects with complement factor H polymorphism.

A common polymorphism in the complement factor H gene (rs1061170, Y402H) is associated with a high risk of age-related macular degeneration (AMD). In the present study we hypothesized that healthy young subjects homozygous for the high-risk haplotype (CC) show abnormal choroidal blood flow (ChBF) re...

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Bibliographic Details
Main Authors: Reinhard Told, Stefan Palkovits, Helmuth Haslacher, Sophie Frantal, Doreen Schmidl, Agnes Boltz, Michael Lasta, Semira Kaya, René M Werkmeister, Gerhard Garhöfer, Leopold Schmetterer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3626650?pdf=render