RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis

RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis

An increase in mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) reportedly attenuates insulin-mediated signaling which participates in the development of brown adipose tissues (BATs). Nevertheless, the effect of MAP4K4 on brown adipogenesis remains largely uncharacterized. In this st...

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Bibliographic Details
Main Authors: Hui-Yu Peng, Yu-Chih Liang, Tse-Hua Tan, Huai-Chia Chuang, Ying-Ju Lin, Jung-Chun Lin
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
alternative splicing
brown adipocytes
MAP4K4
RBM4a
SRSF3
Online Access:http://www.mdpi.com/1422-0067/19/9/2646

Internet

http://www.mdpi.com/1422-0067/19/9/2646

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